{"id":439960,"date":"2023-11-15T14:28:06","date_gmt":"2023-11-15T19:28:06","guid":{"rendered":"https:\/\/www.catster.com\/?p=439960"},"modified":"2024-09-13T00:52:45","modified_gmt":"2024-09-13T04:52:45","slug":"lymphoma-in-cats-vet-answer","status":"publish","type":"post","link":"https:\/\/www.catster.com\/ask-the-vet\/lymphoma-in-cats-vet-answer\/","title":{"rendered":"Lymphoma in Cats: Causes, Signs &#038; Care (Vet Answer)"},"content":{"rendered":"<p>Lymphoma, or lymphosarcoma, is the most common cancer affecting cats. It is a malignant type of cancer affecting the lymphatic system, a network of vessels, nodes, tissues, and organs supporting various bodily functions, including the immune system.<\/p>\n<p>This article will cover more details about this cancer, the signs and causes, and what you can do if your cat gets diagnosed.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-589042\" src=\"https:\/\/www.catster.com\/wp-content\/uploads\/2023\/11\/Catster_Website-dividers_v1-2_Apr-26-2024-07.png\" alt=\"divider 3 paws\" width=\"1200\" height=\"120\" srcset=\"https:\/\/www.catster.com\/wp-content\/uploads\/2023\/11\/Catster_Website-dividers_v1-2_Apr-26-2024-07.png 1200w, https:\/\/www.catster.com\/wp-content\/uploads\/2023\/11\/Catster_Website-dividers_v1-2_Apr-26-2024-07-600x60.png 600w, https:\/\/www.catster.com\/wp-content\/uploads\/2023\/11\/Catster_Website-dividers_v1-2_Apr-26-2024-07-800x80.png 800w, https:\/\/www.catster.com\/wp-content\/uploads\/2023\/11\/Catster_Website-dividers_v1-2_Apr-26-2024-07-768x77.png 768w, https:\/\/www.catster.com\/wp-content\/uploads\/2023\/11\/Catster_Website-dividers_v1-2_Apr-26-2024-07-250x25.png 250w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/><\/p>\n<h2>What Is Lymphoma?<\/h2>\n<p>Lymphoma is a type of cancer of the lymphocytes, a type of blood cell involved in the immune system. This type of cancer also represents an estimated 30% of all new feline cancer diagnoses. Feline lymphoma is closely connected with feline leukemia, a viral infection known as FeLV.<\/p>\n<p>Feline lymphoma is a systemic malignant cancer that affects the lymphatic system and appears most commonly in three sites in cats:<\/p>\n<div class=\"su-list\" style=\"margin-left:0px\">\n<ul>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> Intestinal (gastrointestinal or \u201cGI\u201d) lymphoma is lymphoma of the gastrointestinal tract. This is the most common type of lymphoma seen in cats, accounting for 50\u201370% of feline lymphoma cases. Most gastrointestinal lymphoma cats are senior cats over 9 years old.<\/li>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> Mediastinal lymphoma is lymphoma of the lymphoid organs (e.g., lymph nodes or thymus) in the chest. Most cats with mediastinal lymphoma are young cats affected by the feline leukemia virus (FeLV).<\/li>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> Renal lymphoma is lymphoma of the kidney wherein normal kidney cells are replaced by cancerous cells, leading to signs of kidney failure. Renal lymphoma is also associated with infection with FeLV.<\/li>\n<\/ul>\n<\/div>\n<p>Other types of lymphoma can also occur in cats, including lymphoma of the lymph nodes, brain, nose, and other areas of the body.<\/p>\n<h2>What Are the Signs of Lymphoma in Cats?<\/h2>\n<p>A cat with lymphoma can present with a variety of signs, depending on what organs are involved. Since intestinal lymphoma is the most common version of feline lymphoma, cats often present with clinical signs associated with their gut.<\/p>\n<p>Many cats experience the following:<\/p>\n<div class=\"su-list\" style=\"margin-left:0px\">\n<ul>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> Weight loss<\/li>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> Vomiting<\/li>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> Diarrhea<\/li>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> Issues with appetite (a loss or increase in appetite or experiencing no change)<\/li>\n<\/ul>\n<\/div>\n<p>Bloodwork is often normal in cats with gastrointestinal lymphoma, but abdominal ultrasounds may show abnormalities throughout the intestinal tract (e.g., areas of thickening or discrete masses). However, some cats with gastrointestinal lymphoma can actually appear normal on an abdominal ultrasound.<\/p>\n<p>A cat with mediastinal lymphoma usually experiences respiratory\/breathing problems since the cancer occurs in the chest. Many times, mediastinal lymphoma leads to an accumulation of fluid within the chest, making it very difficult for a cat to breathe normally.<\/p>\n<p>For cats with renal lymphoma, the most common signs associated with kidney failure include:<\/p>\n<div class=\"su-list\" style=\"margin-left:0px\">\n<ul>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> Poor appetite<\/li>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> Weight loss<\/li>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> Increased thirst<\/li>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> Increased urination<\/li>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> Vomiting<\/li>\n<\/ul>\n<\/div>\n<h2>What Are the Causes of Lymphoma in Cats?<\/h2>\n<p>Scientists don\u2019t fully understand the exact cause of feline lymphoma; however, several risk factors have been identified to be associated with lymphoma. These risk factors include:<\/p>\n<div class=\"su-list\" style=\"margin-left:0px\">\n<ul>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> <b><\/b><strong><b>Feline Leukemia Virus (FeLV)<\/b><\/strong>:<a href=\"https:\/\/www.catster.com\/ask-the-vet\/feline-leukemia-virus-in-cats-vet-answer\/\" target=\"_blank\" rel=\"noopener\" data-wpel-link=\"internal\"> FeLV suppresses the immune system<\/a> and can increase the risk of an infected cat developing lymphoma.<\/li>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> <b><\/b><strong><b>Feline Immunodeficiency Virus (FIV)<\/b><\/strong>: FIV also weakens a cat\u2019s immune system and can increase the risk of lymphoma.<\/li>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> <b><\/b><strong><b>Age<\/b><\/strong>: Lymphoma typically shows up in older cats with an average age of 10 years at the time of diagnosis.<\/li>\n<li><i class=\"sui sui-ban\" style=\"color:#BE383E\"><\/i> <b><\/b><strong><b>Environmental Factors: <\/b><\/strong>Environmental factors such as second-hand tobacco smoke can put a cat more at risk for feline lymphoma.<\/li>\n<\/ul>\n<\/div>\n<h2>How Do I Care for a Cat With Lymphoma?<\/h2>\n<p>Feline lymphoma is usually <a href=\"https:\/\/www.catster.com\/guides\/chemotherapy-for-cats-cost\/\" target=\"_blank\" rel=\"noopener\" data-wpel-link=\"internal\">treated with chemotherapy<\/a> or anti-cancer medications. In cases of low-grade lymphoma, cats can be treated with a steroid (prednisolone) and an oral chemotherapy drug (chlorambucil). In the case of high-grade lymphoma, cats are often treated with a series of chemotherapy injections.<\/p>\n<p>Cats tolerate chemotherapy much better than humans, so cats undergoing chemo don\u2019t often appear to have side effects from the medications. The most common side effects for cats undergoing chemotherapy include vomiting, diarrhea, and decreased appetite. These side effects are rare and usually only affect about 10% of feline patients.<\/p>\n<p>Depending on the site of the lymphoma, surgery and\/or radiation therapy may also be recommended for a cat with lymphoma. In most cases, though, surgery or radiation are not ideal options due to the location or extent of the disease.<\/p>\n<p>In some cases, chemotherapy is not a reasonable option due to the cat\u2019s advanced illness or the owner\u2019s finances. In these situations, treatment with steroids (prednisolone) can be used for palliative or hospice care. Owners must understand that steroids help to reduce inflammation and associated clinical signs but do not directly cure the disease.<\/p>\n<p>Cats with lymphoma can also receive other supportive treatments to manage their symptoms, including hydration therapy, nutritional support, anti-nausea medications, and appetite stimulants.<\/p>\n<figure id=\"attachment_115062\" aria-describedby=\"caption-attachment-115062\" style=\"width: 800px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"size-full wp-image-115062\" src=\"https:\/\/www.catster.com\/wp-content\/uploads\/2023\/12\/cat-eating-from-feeding-bowl_Jaromir-Chalabala_Shutterstock.jpg\" alt=\"cat eating from feeding bowl\" width=\"800\" height=\"534\" \/><figcaption id=\"caption-attachment-115062\" class=\"wp-caption-text\">Image Credit: Jaromir Chalabala, Shutterstock<\/figcaption><\/figure>\n<p><img decoding=\"async\" class=\"aligncenter size-large wp-image-1500\" src=\"https:\/\/www.catster.com\/wp-content\/uploads\/2023\/12\/Cats-2-1-1024x102-1.png\" alt=\"3 cat face divider\" width=\"1024\" height=\"102\" \/><\/p>\n<h2>Frequently Asked Questions (FAQ)<\/h2>\n<h3>How is lymphoma diagnosed in cats?<\/h3>\n<p>A veterinarian can use a variety of diagnostic tests to diagnose a cat with lymphoma. Often, baseline blood and urine tests are performed, as well as imaging (X-rays and ultrasound). A small \u201cfine needle aspirate\u201d biopsy can be obtained of abnormal tissue such as an enlarged lymph node, thickened intestinal wall or mass within the intestinal wall, or fluid accumulating in the chest. Sometimes, this test is enough to diagnose lymphoma.<\/p>\n<p>Occasionally, this type of test cannot be performed due to the location of the tissue, or the sample itself ends up being inconclusive. In such cases, a veterinarian may decide to perform surgery to take a larger sample or to remove the abnormal tissue. In the case of gastrointestinal lymphoma, a definitive diagnosis is sometimes achieved through a biopsy of the intestines performed during abdominal surgery.<\/p>\n<p>Once lymphoma is diagnosed, the pathologist can determine if the type of lymphoma is considered high-grade or low-grade based on the characteristics of the cells present in the sample. Low-grade lymphoma has a better prognosis and is more likely to respond to chemotherapy medication.<\/p>\n<p>Following a lymphoma diagnosis, a veterinarian can also perform additional testing to further <a href=\"https:\/\/www.catster.com\/ask-the-vet\/common-cancers-in-cats-vet-answer\/\" target=\"_blank\" rel=\"noopener\" data-wpel-link=\"internal\">characterize the cancer<\/a> to create a more specific treatment plan for the cat.<br \/>\n<div class=\"su-box su-box-style-default pangovet-mention-box\" id=\"\" style=\"border-color:#272470;border-radius:3px\"><div class=\"su-box-title\" style=\"background-color:#5a57a3;color:#FFFFFF;border-top-left-radius:1px;border-top-right-radius:1px\">\ud83d\udc9b \ud83d\ude3a Speak To a Vet Online From the Comfort of Your Couch!<\/div><div class=\"su-box-content su-u-clearfix su-u-trim\" style=\"border-bottom-left-radius:1px;border-bottom-right-radius:1px\">\r\n<img decoding=\"async\" style=\"margin-bottom: 15px;\" class=\"aligncenter wp-image-3542157\" src=\"https:\/\/www.catster.com\/wp-content\/uploads\/2024\/08\/PangoVet_Mention-in-Content_v9_Jun-24-2024.png\" alt=\"PangoVet\" width=\"375\"\/>\r\n\r\n<p style=\"font-weight: 500; text-align: center; line-height: 1.5; font-size: medium !important; margin-bottom: 20px;\">If you need to speak with a vet but can&#8217;t get to one, head over to <a href=\"https:\/\/www.catster.com\/pangovet-general-mention\/\" data-wpel-link=\"internal\" target=\"_blank\"><b>PangoVet<\/b><\/a>. It&#8217;s an online service where you can <b>talk to a vet online<\/b> and get the personalized advice you need for your pet \u2014 all at an affordable price!\r\n<\/p>\r\n<div class=\"su-button-center\"><a href=\"https:\/\/www.catster.com\/pangovet-general-mention\/\" class=\"su-button su-button-style-default\" style=\"color:#FFFFFF;background-color:#FF6600;border-color:#cc5200;border-radius:9px\" target=\"_blank\" rel=\"nofollow\" data-wpel-link=\"internal\"><span style=\"color:#FFFFFF;padding:0px 24px;font-size:18px;line-height:36px;border-color:#ff944d;border-radius:9px;text-shadow:none\"> Click to Speak With a Vet<\/span><\/a><\/div><\/div><\/div>\n<figure id=\"attachment_633549\" aria-describedby=\"caption-attachment-633549\" style=\"width: 1000px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"size-full wp-image-633549\" src=\"https:\/\/www.catster.com\/wp-content\/uploads\/2023\/11\/veterinarians-examining-a-grey-cat_Juice-Flair_Shutterstock.jpg\" alt=\"veterinarians examining a grey cat\" width=\"1000\" height=\"667\" srcset=\"https:\/\/www.catster.com\/wp-content\/uploads\/2023\/11\/veterinarians-examining-a-grey-cat_Juice-Flair_Shutterstock.jpg 1000w, https:\/\/www.catster.com\/wp-content\/uploads\/2023\/11\/veterinarians-examining-a-grey-cat_Juice-Flair_Shutterstock-600x400.jpg 600w, https:\/\/www.catster.com\/wp-content\/uploads\/2023\/11\/veterinarians-examining-a-grey-cat_Juice-Flair_Shutterstock-800x534.jpg 800w, https:\/\/www.catster.com\/wp-content\/uploads\/2023\/11\/veterinarians-examining-a-grey-cat_Juice-Flair_Shutterstock-768x512.jpg 768w, https:\/\/www.catster.com\/wp-content\/uploads\/2023\/11\/veterinarians-examining-a-grey-cat_Juice-Flair_Shutterstock-250x167.jpg 250w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><figcaption id=\"caption-attachment-633549\" class=\"wp-caption-text\">Image Credit: Juice Flair, Shutterstock<\/figcaption><\/figure>\n<h3>What is the prognosis for cats with lymphoma?<\/h3>\n<p>The prognosis for feline lymphoma is dependent on the type, location, and extent of lymphoma, the cat\u2019s co-infections (e.g., with FeLV or FIV), how sick they are at the time of diagnosis, and how soon treatment can be initiated. Fortunately, most cases of feline intestinal lymphoma (the most common type) are low-grade lymphoma. Most cats (about 70%) who are treated for this type of lymphoma go into remission from the disease.<\/p>\n<p>Cat owners need to understand that feline lymphoma is never completely cured, but remission can be achieved. With treatment, remission for low-grade lymphoma can be, on average, from 2\u20133 years. For high-grade lymphoma cases, cats typically do not respond well to treatment. Cats with high-grade lymphoma achieve remission at a much lower rate (25\u201350%) compared to low-grade cases. Even when they do reach remission, it typically only lasts between 2\u20139 months.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-1502\" src=\"https:\/\/www.catster.com\/wp-content\/uploads\/2023\/12\/Cat-7-1-1.png\" alt=\"cat + line divider\" width=\"475\" height=\"120\" \/><\/p>\n<h2>Conclusion<\/h2>\n<p>Feline lymphoma is one of the most common cancers in cats. With early diagnosis, many cats can achieve remission following treatment initiation. If you suspect your cat may have lymphoma, it is important to consult your cat\u2019s veterinarian for evaluation and testing.<\/p>\n<ul>\n<li><strong>See also:\u00a0<\/strong><a href=\"https:\/\/www.catster.com\/lifestyle\/cat-lymph-nodes\/\" target=\"_blank\" rel=\"noopener\" data-wpel-link=\"internal\">Cat Lymph Nodes: Vet-Verified Health Facts, Guide &amp; Diagram<\/a><\/li>\n<\/ul>\n<div class=\"su-accordion su-u-trim\"> <div class=\"su-spoiler su-spoiler-style-default su-spoiler-icon-plus su-spoiler-closed\" data-scroll-offset=\"0\" data-anchor-in-url=\"no\"><div class=\"su-spoiler-title\" tabindex=\"0\" role=\"button\"><span class=\"su-spoiler-icon\"><\/span>Sources<\/div><div class=\"su-spoiler-content su-u-clearfix su-u-trim\">\n<ul>\n<li><a href=\"https:\/\/vcahospitals.com\/know-your-pet\/lymphoma-in-cats\" data-wpel-link=\"external\" target=\"_blank\"><u>https:\/\/vcahospitals.com\/know-your-pet\/lymphoma-in-cats <\/u><\/a><\/li>\n<li><a href=\"https:\/\/www.vet.cornell.edu\/departments-centers-and-institutes\/cornell-feline-health-center\/health-information\/feline-health-topics\/lymphoma\" data-wpel-link=\"external\" target=\"_blank\"><u>https:\/\/www.vet.cornell.edu\/departments-centers-and-institutes\/cornell-feline-health-center\/health-information\/feline-health-topics\/lymphoma <\/u><\/a><\/li>\n<li><a href=\"https:\/\/hospital.cvm.ncsu.edu\/services\/small-animals\/cancer-oncology\/oncology\/feline-lymphoma\/\" data-wpel-link=\"external\" target=\"_blank\"><u>https:\/\/hospital.cvm.ncsu.edu\/services\/small-animals\/cancer-oncology\/oncology\/feline-lymphoma\/ <\/u><\/a><\/li>\n<li><a href=\"https:\/\/icatcare.org\/advice\/lymphoma\/\" target=\"_blank\" rel=\"noopener\" data-wpel-link=\"external\">https:\/\/icatcare.org\/advice\/lymphoma\/<\/a><\/li>\n<\/ul>\n<\/div><\/div> <\/div>\n<hr \/>\n<p>Featured Image Credit: PRESSLAB, Shutterstock<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lymphoma, or lymphosarcoma, is the most common cancer affecting cats. It is a malignant type of cancer affecting the lymphatic system, a network of vessels, nodes, tissues, and organs supporting various bodily functions, including the immune system. This article will cover more details about this cancer, the signs and causes, and what you can do [&hellip;]<\/p>\n","protected":false},"author":3896,"featured_media":407570,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"","wprm-recipe-roundup-name":"","wprm-recipe-roundup-description":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ep_exclude_from_search":false,"footnotes":""},"categories":[405],"tags":[398,402],"class_list":["post-439960","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ask-the-vet","tag-from-excitedcats","tag-vet-approved"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Lymphoma in Cats: Causes, Signs &amp; Care (Vet Answer) - Catster<\/title>\n<meta name=\"description\" content=\"Feline lymphoma is one of the most common cancers in cats. 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